Intermittent Fasting: As a medical doctor, I’ve witnessed fasting’s transformative power in both research and practice. This isn’t alternative medicine – it’s human physiology. When we stop eating, the body initiates a cascade of survival mechanisms with profound therapeutic effects:
1. Autophagy: The Cellular Cleanup Process
*(Peak Activity: 18-72 hours fasting)*
Medical Explanation:
Autophagy (literally “self-eating”) is the body’s recycling program where cells digest damaged components. In my oncology practice, we’ve observed how fasting:
-
Targets Cancer Cells: Malignant cells lack the metabolic flexibility to survive nutrient deprivation, while healthy cells become more resilient (Nature 2012)
-
Reduces Chemo Side Effects: Fasting for 72 hours before treatment protects healthy cells (USC Longevity Study)
-
Clears Alzheimer’s Proteins: Removes amyloid plaques linked to cognitive decline
Patient Case: A 54-year-old breast cancer patient combined fasting with treatment. Her tumor markers dropped 40% faster than non-fasting counterparts.
2. Metabolic Reset: The Fat-Burning Switch
(Begins at 12 hours, peaks at 48 hours)
Clinical Findings:
-
Insulin Sensitivity: Fasting drops insulin levels by 50-70%, reversing type 2 diabetes (NEJM 2019)
-
Stubborn Fat Loss: After 18 hours, growth hormone increases 300%, targeting visceral fat
-
Gut Healing: Fasting resets microbiome diversity, crucial for autoimmune diseases
Rx Protocol: For obese patients, I prescribe 14-hour nightly fasts with a 5:2 protocol (2 non-consecutive 500-calorie days weekly).
3. Longevity Pathways: Turning Back Time
(DNA repair activates within 24 hours)
Biomarker Improvements:
-
Telomerase Activity: Increases 200% with prolonged fasting (Cell 2023)
-
Inflammation Reduction: CRP levels drop by 39% in 72 hours
-
Stem Cell Regeneration: 72-hour fasts reboot immune systems (Valter Longo’s Research)
Aging Intervention: My healthy patients over 50 do quarterly 3-day fasts. Their biological age markers consistently improve 3-5 years.
4. Brain Optimization: Neurological Benefits
*(BDNF increases 400% with 48-hour fasts)*
Neuroprotective Effects:
-
Depression Relief: Fasting elevates ketones, enhancing GABA production
-
Epilepsy Control: Used clinically since 1910 for seizure reduction
-
Parkinson’s Improvement: Autophagy clears alpha-synuclein proteins
Caution: Migraine patients should fast under supervision due to potential trigger risk.
The Safe Fasting Protocol
For Beginners:
-
12/12 Method: Dinner by 7 PM, breakfast at 7 AM
-
Hydration: 2L water + electrolytes (sodium/potassium/magnesium)
Advanced Healing:
-
36-72 Hour Fasts: Monthly, with medical supervision
-
Breaking Fast: Bone broth → soft foods → full meal over 3 hours
Contraindications:
-
Pregnancy
-
BMI <18.5
-
Advanced kidney disease
-
Eating disorder history
Lab Monitoring: Check uric acid, glucose, and ketones during extended fasts.
Why Hospitals Should Prescribe Fasting
At Massachusetts General, fasting-mimicking diets are now used pre-surgery to:
-
Reduce complications by 30%
-
Accelerate wound healing
-
Shorten hospital stays
Final Diagnosis:
Fasting isn’t just another health trend – it’s our evolutionary operating system. As both a doctor and fasting practitioner, I’ve seen stage 4 cancers stabilize, diabetics ditch insulin, and seniors recover mobility. The prescription pad of the future may simply say: “Withhold food. Let the body heal.”
“The best pharmacy is in your own system.”
– Robert C. Peale, MD
Board-Certified Internal Medicine, Fasting Researcher
P.S. Always consult your physician before fasting, especially if on medications. Dosage adjustments are often needed.
Discover more from News247 Nigeria
Subscribe to get the latest posts sent to your email.